Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement.
Identifieur interne : 000915 ( Main/Exploration ); précédent : 000914; suivant : 000916Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement.
Auteurs : Matthias Guckenberger [Suisse] ; Claus Belka [Allemagne] ; Andrea Bezjak [Canada] ; Jeffrey Bradley [États-Unis] ; Megan E. Daly [États-Unis] ; Dirk Deruysscher [Pays-Bas] ; Rafal Dziadziuszko [Pologne] ; Corinne Faivre-Finn [Royaume-Uni] ; Michael Flentje [Allemagne] ; Elizabeth Gore [États-Unis] ; Kristin A. Higgins [États-Unis] ; Puneeth Iyengar [États-Unis] ; Brian D. Kavanagh [États-Unis] ; Sameera Kumar [États-Unis] ; Cecile Le Pechoux [France] ; Yolande Lievens [Belgique] ; Karin Lindberg [Suède] ; Fiona Mcdonald [Royaume-Uni] ; Sara Ramella [Italie] ; Ramesh Rengan [États-Unis] ; Umberto Ricardi [Italie] ; Andreas Rimner [États-Unis] ; George B. Rodrigues [Canada] ; Steven E. Schild [États-Unis] ; Suresh Senan [Pays-Bas] ; Charles B. Simone [États-Unis] ; Ben J. Slotman [Pays-Bas] ; Martin Stuschke [Allemagne] ; Greg Videtic [États-Unis] ; Joachim Widder [Autriche] ; Sue S. Yom [États-Unis] ; David Palma [Canada]Source :
- International journal of radiation oncology, biology, physics [ 1879-355X ] ; 2020.
Descripteurs français
- KwdFr :
- Consensus (MeSH), Gestion du risque (MeSH), Guides de bonnes pratiques cliniques comme sujet (MeSH), Humains (MeSH), Infections à coronavirus (épidémiologie), Oncologie médicale (MeSH), Pandémies (MeSH), Pneumopathie virale (épidémiologie), Sociétés médicales (MeSH), Triage (MeSH), Tumeurs du poumon (radiothérapie).
- MESH :
- radiothérapie : Tumeurs du poumon.
- épidémiologie : Infections à coronavirus, Pneumopathie virale.
- Consensus, Gestion du risque, Guides de bonnes pratiques cliniques comme sujet, Humains, Oncologie médicale, Pandémies, Sociétés médicales, Triage.
English descriptors
- KwdEn :
- MESH :
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- radiotherapy : Lung Neoplasms.
- Consensus, Humans, Medical Oncology, Pandemics, Practice Guidelines as Topic, Risk Management, Societies, Medical, Triage.
Abstract
BACKGROUND
The COVID-19 pandemic has caused radiotherapy resource pressures and led to increased risks for lung cancer patients and healthcare staff. An international group of experts in lung cancer radiotherapy established this practice recommendation pertaining to whether and how to adapt radiotherapy for lung cancer in the COVID-19 pandemic.
METHODS
For this ESTRO & ASTRO endorsed project, 32 experts in lung cancer radiotherapy contributed to a modified Delphi consensus process. We assessed potential adaptations of radiotherapy in two pandemic scenarios. The first, an early pandemic scenario of risk mitigation, is characterized by an altered risk-benefit ratio of radiotherapy for lung cancer patients due to their increased susceptibility for severe COVID-19 infection, and minimization of patient travelling and exposure of radiotherapy staff. The second, a later pandemic scenario, is characterized by reduced radiotherapy resources requiring patient triage. Six common lung cancer cases were assessed for both scenarios: peripherally located stage I NSCLC, locally advanced NSCLC, postoperative radiotherapy after resection of pN2 NSCLC, thoracic radiotherapy and prophylactic cranial irradiation for limited stage SCLC and palliative thoracic radiotherapy for stage IV NSCLC.
RESULTS
In a risk-mitigation pandemic scenario, efforts should be made not to compromise the prognosis of lung cancer patients by departing from guideline-recommended radiotherapy practice. In that same scenario, postponement or interruption of radiotherapy treatment of COVID-19 positive patients is generally recommended to avoid exposure of cancer patients and staff to an increased risk of COVID-19 infection. In a severe pandemic scenario characterized by reduced resources, if patients must be triaged, important factors for triage include potential for cure, relative benefit of radiation, life expectancy, and performance status. Case-specific consensus recommendations regarding multimodality treatment strategies and fractionation of radiotherapy are provided.
CONCLUSION
This joint ESTRO-ASTRO practice recommendation established pragmatic and balanced consensus recommendations in common clinical scenarios of radiotherapy for lung cancer in order to address the challenges of the COVID-19 pandemic.
DOI: 10.1016/j.ijrobp.2020.05.012
PubMed: 32589990
Affiliations:
- Allemagne, Autriche, Belgique, Canada, France, Italie, Pays-Bas, Pologne, Royaume-Uni, Suisse, Suède, États-Unis
- Angleterre, Canton de Zurich, Grand Londres, Grand Manchester, Ontario, Pennsylvanie, Svealand, Texas, État de New York
- Dallas, Londres, Manchester, Philadelphie, Stockholm, Toronto, Villejuif, Zurich
- Université de Toronto, Université de Zurich
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement.</title><author><name sortKey="Guckenberger, Matthias" sort="Guckenberger, Matthias" uniqKey="Guckenberger M" first="Matthias" last="Guckenberger">Matthias Guckenberger</name><affiliation wicri:level="4"><nlm:affiliation>Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Switzerland. Electronic address: Matthias.Guckenberger@usz.ch.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Radiation Oncology, University Hospital Zurich, University of Zurich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Belka, Claus" sort="Belka, Claus" uniqKey="Belka C" first="Claus" last="Belka">Claus Belka</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, LMU Klinikum, LMU Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, LMU Klinikum, LMU Munich</wicri:regionArea><wicri:noRegion>LMU Munich</wicri:noRegion><wicri:noRegion>LMU Munich</wicri:noRegion><wicri:noRegion>LMU Munich</wicri:noRegion></affiliation></author><author><name sortKey="Bezjak, Andrea" sort="Bezjak, Andrea" uniqKey="Bezjak A" first="Andrea" last="Bezjak">Andrea Bezjak</name><affiliation wicri:level="4"><nlm:affiliation>Department of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto</wicri:regionArea><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Bradley, Jeffrey" sort="Bradley, Jeffrey" uniqKey="Bradley J" first="Jeffrey" last="Bradley">Jeffrey Bradley</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Daly, Megan E" sort="Daly, Megan E" uniqKey="Daly M" first="Megan E" last="Daly">Megan E. Daly</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, Sacramento, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, Sacramento</wicri:regionArea><wicri:noRegion>Sacramento</wicri:noRegion></affiliation></author><author><name sortKey="Deruysscher, Dirk" sort="Deruysscher, Dirk" uniqKey="Deruysscher D" first="Dirk" last="Deruysscher">Dirk Deruysscher</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology (Maastro Clinic), Maastricht University Medical Center(+), GROW Research Institute, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology (Maastro Clinic), Maastricht University Medical Center(+), GROW Research Institute</wicri:regionArea><wicri:noRegion>GROW Research Institute</wicri:noRegion></affiliation></author><author><name sortKey="Dziadziuszko, Rafal" sort="Dziadziuszko, Rafal" uniqKey="Dziadziuszko R" first="Rafal" last="Dziadziuszko">Rafal Dziadziuszko</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Oncology and Radiotherapy, Medical University of Gdansk, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Dept. of Oncology and Radiotherapy, Medical University of Gdansk</wicri:regionArea><wicri:noRegion>Medical University of Gdansk</wicri:noRegion></affiliation></author><author><name sortKey="Faivre Finn, Corinne" sort="Faivre Finn, Corinne" uniqKey="Faivre Finn C" first="Corinne" last="Faivre-Finn">Corinne Faivre-Finn</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Flentje, Michael" sort="Flentje, Michael" uniqKey="Flentje M" first="Michael" last="Flentje">Michael Flentje</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University Hospital Würzburg, JMU Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, University Hospital Würzburg, JMU Würzburg</wicri:regionArea><wicri:noRegion>JMU Würzburg</wicri:noRegion><wicri:noRegion>JMU Würzburg</wicri:noRegion><wicri:noRegion>JMU Würzburg</wicri:noRegion></affiliation></author><author><name sortKey="Gore, Elizabeth" sort="Gore, Elizabeth" uniqKey="Gore E" first="Elizabeth" last="Gore">Elizabeth Gore</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Medical College of Wisconsin and Zablocki VAMC, Milwaukee, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Medical College of Wisconsin and Zablocki VAMC, Milwaukee</wicri:regionArea><wicri:noRegion>Milwaukee</wicri:noRegion></affiliation></author><author><name sortKey="Higgins, Kristin A" sort="Higgins, Kristin A" uniqKey="Higgins K" first="Kristin A" last="Higgins">Kristin A. Higgins</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Iyengar, Puneeth" sort="Iyengar, Puneeth" uniqKey="Iyengar P" first="Puneeth" last="Iyengar">Puneeth Iyengar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, UT Southwestern Medical Center, Dallas</wicri:regionArea><placeName><settlement type="city">Dallas</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Kavanagh, Brian D" sort="Kavanagh, Brian D" uniqKey="Kavanagh B" first="Brian D" last="Kavanagh">Brian D. Kavanagh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of Colorado, Aurora, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of Colorado, Aurora</wicri:regionArea><wicri:noRegion>Aurora</wicri:noRegion></affiliation></author><author><name sortKey="Kumar, Sameera" sort="Kumar, Sameera" uniqKey="Kumar S" first="Sameera" last="Kumar">Sameera Kumar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia</wicri:regionArea><placeName><settlement type="city">Philadelphie</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Le Pechoux, Cecile" sort="Le Pechoux, Cecile" uniqKey="Le Pechoux C" first="Cecile" last="Le Pechoux">Cecile Le Pechoux</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif</wicri:regionArea><placeName><settlement type="city">Villejuif</settlement></placeName></affiliation></author><author><name sortKey="Lievens, Yolande" sort="Lievens, Yolande" uniqKey="Lievens Y" first="Yolande" last="Lievens">Yolande Lievens</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Ghent University Hospital and Ghent University, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Radiation Oncology, Ghent University Hospital and Ghent University</wicri:regionArea><wicri:noRegion>Ghent University Hospital and Ghent University</wicri:noRegion></affiliation></author><author><name sortKey="Lindberg, Karin" sort="Lindberg, Karin" uniqKey="Lindberg K" first="Karin" last="Lindberg">Karin Lindberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Head, Neck, Lung and Skin Cancer, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Head, Neck, Lung and Skin Cancer, Theme Cancer, Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Mcdonald, Fiona" sort="Mcdonald, Fiona" uniqKey="Mcdonald F" first="Fiona" last="Mcdonald">Fiona Mcdonald</name><affiliation wicri:level="3"><nlm:affiliation>Royal Marsden Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Royal Marsden Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ramella, Sara" sort="Ramella, Sara" uniqKey="Ramella S" first="Sara" last="Ramella">Sara Ramella</name><affiliation wicri:level="1"><nlm:affiliation>Radiation Oncology, Campus Bio-Medico University of Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Radiation Oncology, Campus Bio-Medico University of Rome</wicri:regionArea><wicri:noRegion>Campus Bio-Medico University of Rome</wicri:noRegion></affiliation></author><author><name sortKey="Rengan, Ramesh" sort="Rengan, Ramesh" uniqKey="Rengan R" first="Ramesh" last="Rengan">Ramesh Rengan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of Washington School of Medicine, Seattle, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of Washington School of Medicine, Seattle</wicri:regionArea><wicri:noRegion>Seattle</wicri:noRegion></affiliation></author><author><name sortKey="Ricardi, Umberto" sort="Ricardi, Umberto" uniqKey="Ricardi U" first="Umberto" last="Ricardi">Umberto Ricardi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, University of Turin, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Oncology, University of Turin</wicri:regionArea><wicri:noRegion>University of Turin</wicri:noRegion></affiliation></author><author><name sortKey="Rimner, Andreas" sort="Rimner, Andreas" uniqKey="Rimner A" first="Andreas" last="Rimner">Andreas Rimner</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Rodrigues, George B" sort="Rodrigues, George B" uniqKey="Rodrigues G" first="George B" last="Rodrigues">George B. Rodrigues</name><affiliation wicri:level="3"><nlm:affiliation>Division of Radiation Oncology, Western University, London, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Radiation Oncology, Western University, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Schild, Steven E" sort="Schild, Steven E" uniqKey="Schild S" first="Steven E" last="Schild">Steven E. Schild</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Mayo Clinic, Phoenix, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Mayo Clinic, Phoenix</wicri:regionArea><wicri:noRegion>Phoenix</wicri:noRegion></affiliation></author><author><name sortKey="Senan, Suresh" sort="Senan, Suresh" uniqKey="Senan S" first="Suresh" last="Senan">Suresh Senan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Amsterdam UMC, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology, Amsterdam UMC</wicri:regionArea><wicri:noRegion>Amsterdam UMC</wicri:noRegion></affiliation></author><author><name sortKey="Simone, Charles B" sort="Simone, Charles B" uniqKey="Simone C" first="Charles B" last="Simone">Charles B. Simone</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, New York Proton Center and Memorial Sloan Kettering Cancer Center, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, New York Proton Center and Memorial Sloan Kettering Cancer Center</wicri:regionArea><wicri:noRegion>New York Proton Center and Memorial Sloan Kettering Cancer Center</wicri:noRegion></affiliation></author><author><name sortKey="Slotman, Ben J" sort="Slotman, Ben J" uniqKey="Slotman B" first="Ben J" last="Slotman">Ben J. Slotman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Amsterdam UMC, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology, Amsterdam UMC</wicri:regionArea><wicri:noRegion>Amsterdam UMC</wicri:noRegion></affiliation></author><author><name sortKey="Stuschke, Martin" sort="Stuschke, Martin" uniqKey="Stuschke M" first="Martin" last="Stuschke">Martin Stuschke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiotherapy, University Duisburg-Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiotherapy, University Duisburg-Essen</wicri:regionArea><wicri:noRegion>University Duisburg-Essen</wicri:noRegion><wicri:noRegion>University Duisburg-Essen</wicri:noRegion><wicri:noRegion>University Duisburg-Essen</wicri:noRegion></affiliation></author><author><name sortKey="Videtic, Greg" sort="Videtic, Greg" uniqKey="Videtic G" first="Greg" last="Videtic">Greg Videtic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Cleveland Clinic Lerner College of Medicine of Case Western University, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Cleveland Clinic Lerner College of Medicine of Case Western University</wicri:regionArea><wicri:noRegion>Cleveland Clinic Lerner College of Medicine of Case Western University</wicri:noRegion></affiliation></author><author><name sortKey="Widder, Joachim" sort="Widder, Joachim" uniqKey="Widder J" first="Joachim" last="Widder">Joachim Widder</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna</wicri:regionArea><wicri:noRegion>Medical University of Vienna</wicri:noRegion></affiliation></author><author><name sortKey="Yom, Sue S" sort="Yom, Sue S" uniqKey="Yom S" first="Sue S" last="Yom">Sue S. Yom</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of California San Francisco, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of California San Francisco</wicri:regionArea><wicri:noRegion>University of California San Francisco</wicri:noRegion></affiliation></author><author><name sortKey="Palma, David" sort="Palma, David" uniqKey="Palma D" first="David" last="Palma">David Palma</name><affiliation wicri:level="3"><nlm:affiliation>Division of Radiation Oncology, Western University, London, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Radiation Oncology, Western University, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32589990</idno><idno type="pmid">32589990</idno><idno type="doi">10.1016/j.ijrobp.2020.05.012</idno><idno type="wicri:Area/Main/Corpus">000B90</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000B90</idno><idno type="wicri:Area/Main/Curation">000B90</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000B90</idno><idno type="wicri:Area/Main/Exploration">000B90</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement.</title><author><name sortKey="Guckenberger, Matthias" sort="Guckenberger, Matthias" uniqKey="Guckenberger M" first="Matthias" last="Guckenberger">Matthias Guckenberger</name><affiliation wicri:level="4"><nlm:affiliation>Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Switzerland. Electronic address: Matthias.Guckenberger@usz.ch.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Radiation Oncology, University Hospital Zurich, University of Zurich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Belka, Claus" sort="Belka, Claus" uniqKey="Belka C" first="Claus" last="Belka">Claus Belka</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, LMU Klinikum, LMU Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, LMU Klinikum, LMU Munich</wicri:regionArea><wicri:noRegion>LMU Munich</wicri:noRegion><wicri:noRegion>LMU Munich</wicri:noRegion><wicri:noRegion>LMU Munich</wicri:noRegion></affiliation></author><author><name sortKey="Bezjak, Andrea" sort="Bezjak, Andrea" uniqKey="Bezjak A" first="Andrea" last="Bezjak">Andrea Bezjak</name><affiliation wicri:level="4"><nlm:affiliation>Department of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto</wicri:regionArea><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Bradley, Jeffrey" sort="Bradley, Jeffrey" uniqKey="Bradley J" first="Jeffrey" last="Bradley">Jeffrey Bradley</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Daly, Megan E" sort="Daly, Megan E" uniqKey="Daly M" first="Megan E" last="Daly">Megan E. Daly</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, Sacramento, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, Sacramento</wicri:regionArea><wicri:noRegion>Sacramento</wicri:noRegion></affiliation></author><author><name sortKey="Deruysscher, Dirk" sort="Deruysscher, Dirk" uniqKey="Deruysscher D" first="Dirk" last="Deruysscher">Dirk Deruysscher</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology (Maastro Clinic), Maastricht University Medical Center(+), GROW Research Institute, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology (Maastro Clinic), Maastricht University Medical Center(+), GROW Research Institute</wicri:regionArea><wicri:noRegion>GROW Research Institute</wicri:noRegion></affiliation></author><author><name sortKey="Dziadziuszko, Rafal" sort="Dziadziuszko, Rafal" uniqKey="Dziadziuszko R" first="Rafal" last="Dziadziuszko">Rafal Dziadziuszko</name><affiliation wicri:level="1"><nlm:affiliation>Dept. of Oncology and Radiotherapy, Medical University of Gdansk, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Dept. of Oncology and Radiotherapy, Medical University of Gdansk</wicri:regionArea><wicri:noRegion>Medical University of Gdansk</wicri:noRegion></affiliation></author><author><name sortKey="Faivre Finn, Corinne" sort="Faivre Finn, Corinne" uniqKey="Faivre Finn C" first="Corinne" last="Faivre-Finn">Corinne Faivre-Finn</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Flentje, Michael" sort="Flentje, Michael" uniqKey="Flentje M" first="Michael" last="Flentje">Michael Flentje</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University Hospital Würzburg, JMU Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, University Hospital Würzburg, JMU Würzburg</wicri:regionArea><wicri:noRegion>JMU Würzburg</wicri:noRegion><wicri:noRegion>JMU Würzburg</wicri:noRegion><wicri:noRegion>JMU Würzburg</wicri:noRegion></affiliation></author><author><name sortKey="Gore, Elizabeth" sort="Gore, Elizabeth" uniqKey="Gore E" first="Elizabeth" last="Gore">Elizabeth Gore</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Medical College of Wisconsin and Zablocki VAMC, Milwaukee, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Medical College of Wisconsin and Zablocki VAMC, Milwaukee</wicri:regionArea><wicri:noRegion>Milwaukee</wicri:noRegion></affiliation></author><author><name sortKey="Higgins, Kristin A" sort="Higgins, Kristin A" uniqKey="Higgins K" first="Kristin A" last="Higgins">Kristin A. Higgins</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Iyengar, Puneeth" sort="Iyengar, Puneeth" uniqKey="Iyengar P" first="Puneeth" last="Iyengar">Puneeth Iyengar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, UT Southwestern Medical Center, Dallas</wicri:regionArea><placeName><settlement type="city">Dallas</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Kavanagh, Brian D" sort="Kavanagh, Brian D" uniqKey="Kavanagh B" first="Brian D" last="Kavanagh">Brian D. Kavanagh</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of Colorado, Aurora, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of Colorado, Aurora</wicri:regionArea><wicri:noRegion>Aurora</wicri:noRegion></affiliation></author><author><name sortKey="Kumar, Sameera" sort="Kumar, Sameera" uniqKey="Kumar S" first="Sameera" last="Kumar">Sameera Kumar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia</wicri:regionArea><placeName><settlement type="city">Philadelphie</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Le Pechoux, Cecile" sort="Le Pechoux, Cecile" uniqKey="Le Pechoux C" first="Cecile" last="Le Pechoux">Cecile Le Pechoux</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif</wicri:regionArea><placeName><settlement type="city">Villejuif</settlement></placeName></affiliation></author><author><name sortKey="Lievens, Yolande" sort="Lievens, Yolande" uniqKey="Lievens Y" first="Yolande" last="Lievens">Yolande Lievens</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Ghent University Hospital and Ghent University, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Radiation Oncology, Ghent University Hospital and Ghent University</wicri:regionArea><wicri:noRegion>Ghent University Hospital and Ghent University</wicri:noRegion></affiliation></author><author><name sortKey="Lindberg, Karin" sort="Lindberg, Karin" uniqKey="Lindberg K" first="Karin" last="Lindberg">Karin Lindberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Head, Neck, Lung and Skin Cancer, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Head, Neck, Lung and Skin Cancer, Theme Cancer, Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Mcdonald, Fiona" sort="Mcdonald, Fiona" uniqKey="Mcdonald F" first="Fiona" last="Mcdonald">Fiona Mcdonald</name><affiliation wicri:level="3"><nlm:affiliation>Royal Marsden Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Royal Marsden Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ramella, Sara" sort="Ramella, Sara" uniqKey="Ramella S" first="Sara" last="Ramella">Sara Ramella</name><affiliation wicri:level="1"><nlm:affiliation>Radiation Oncology, Campus Bio-Medico University of Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Radiation Oncology, Campus Bio-Medico University of Rome</wicri:regionArea><wicri:noRegion>Campus Bio-Medico University of Rome</wicri:noRegion></affiliation></author><author><name sortKey="Rengan, Ramesh" sort="Rengan, Ramesh" uniqKey="Rengan R" first="Ramesh" last="Rengan">Ramesh Rengan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of Washington School of Medicine, Seattle, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of Washington School of Medicine, Seattle</wicri:regionArea><wicri:noRegion>Seattle</wicri:noRegion></affiliation></author><author><name sortKey="Ricardi, Umberto" sort="Ricardi, Umberto" uniqKey="Ricardi U" first="Umberto" last="Ricardi">Umberto Ricardi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, University of Turin, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Oncology, University of Turin</wicri:regionArea><wicri:noRegion>University of Turin</wicri:noRegion></affiliation></author><author><name sortKey="Rimner, Andreas" sort="Rimner, Andreas" uniqKey="Rimner A" first="Andreas" last="Rimner">Andreas Rimner</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Rodrigues, George B" sort="Rodrigues, George B" uniqKey="Rodrigues G" first="George B" last="Rodrigues">George B. Rodrigues</name><affiliation wicri:level="3"><nlm:affiliation>Division of Radiation Oncology, Western University, London, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Radiation Oncology, Western University, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Schild, Steven E" sort="Schild, Steven E" uniqKey="Schild S" first="Steven E" last="Schild">Steven E. Schild</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Mayo Clinic, Phoenix, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Mayo Clinic, Phoenix</wicri:regionArea><wicri:noRegion>Phoenix</wicri:noRegion></affiliation></author><author><name sortKey="Senan, Suresh" sort="Senan, Suresh" uniqKey="Senan S" first="Suresh" last="Senan">Suresh Senan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Amsterdam UMC, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology, Amsterdam UMC</wicri:regionArea><wicri:noRegion>Amsterdam UMC</wicri:noRegion></affiliation></author><author><name sortKey="Simone, Charles B" sort="Simone, Charles B" uniqKey="Simone C" first="Charles B" last="Simone">Charles B. Simone</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, New York Proton Center and Memorial Sloan Kettering Cancer Center, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, New York Proton Center and Memorial Sloan Kettering Cancer Center</wicri:regionArea><wicri:noRegion>New York Proton Center and Memorial Sloan Kettering Cancer Center</wicri:noRegion></affiliation></author><author><name sortKey="Slotman, Ben J" sort="Slotman, Ben J" uniqKey="Slotman B" first="Ben J" last="Slotman">Ben J. Slotman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Amsterdam UMC, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Radiation Oncology, Amsterdam UMC</wicri:regionArea><wicri:noRegion>Amsterdam UMC</wicri:noRegion></affiliation></author><author><name sortKey="Stuschke, Martin" sort="Stuschke, Martin" uniqKey="Stuschke M" first="Martin" last="Stuschke">Martin Stuschke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiotherapy, University Duisburg-Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiotherapy, University Duisburg-Essen</wicri:regionArea><wicri:noRegion>University Duisburg-Essen</wicri:noRegion><wicri:noRegion>University Duisburg-Essen</wicri:noRegion><wicri:noRegion>University Duisburg-Essen</wicri:noRegion></affiliation></author><author><name sortKey="Videtic, Greg" sort="Videtic, Greg" uniqKey="Videtic G" first="Greg" last="Videtic">Greg Videtic</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Cleveland Clinic Lerner College of Medicine of Case Western University, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Cleveland Clinic Lerner College of Medicine of Case Western University</wicri:regionArea><wicri:noRegion>Cleveland Clinic Lerner College of Medicine of Case Western University</wicri:noRegion></affiliation></author><author><name sortKey="Widder, Joachim" sort="Widder, Joachim" uniqKey="Widder J" first="Joachim" last="Widder">Joachim Widder</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna</wicri:regionArea><wicri:noRegion>Medical University of Vienna</wicri:noRegion></affiliation></author><author><name sortKey="Yom, Sue S" sort="Yom, Sue S" uniqKey="Yom S" first="Sue S" last="Yom">Sue S. Yom</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, University of California San Francisco, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, University of California San Francisco</wicri:regionArea><wicri:noRegion>University of California San Francisco</wicri:noRegion></affiliation></author><author><name sortKey="Palma, David" sort="Palma, David" uniqKey="Palma D" first="David" last="Palma">David Palma</name><affiliation wicri:level="3"><nlm:affiliation>Division of Radiation Oncology, Western University, London, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Radiation Oncology, Western University, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j">International journal of radiation oncology, biology, physics</title><idno type="eISSN">1879-355X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Consensus (MeSH)</term><term>Coronavirus Infections (epidemiology)</term><term>Humans (MeSH)</term><term>Lung Neoplasms (radiotherapy)</term><term>Medical Oncology (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (epidemiology)</term><term>Practice Guidelines as Topic (MeSH)</term><term>Risk Management (MeSH)</term><term>Societies, Medical (MeSH)</term><term>Triage (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Consensus (MeSH)</term><term>Gestion du risque (MeSH)</term><term>Guides de bonnes pratiques cliniques comme sujet (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (épidémiologie)</term><term>Oncologie médicale (MeSH)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (épidémiologie)</term><term>Sociétés médicales (MeSH)</term><term>Triage (MeSH)</term><term>Tumeurs du poumon (radiothérapie)</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Lung Neoplasms</term></keywords><keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Tumeurs du poumon</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Consensus</term><term>Humans</term><term>Medical Oncology</term><term>Pandemics</term><term>Practice Guidelines as Topic</term><term>Risk Management</term><term>Societies, Medical</term><term>Triage</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Consensus</term><term>Gestion du risque</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Oncologie médicale</term><term>Pandémies</term><term>Sociétés médicales</term><term>Triage</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>The COVID-19 pandemic has caused radiotherapy resource pressures and led to increased risks for lung cancer patients and healthcare staff. An international group of experts in lung cancer radiotherapy established this practice recommendation pertaining to whether and how to adapt radiotherapy for lung cancer in the COVID-19 pandemic.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>For this ESTRO & ASTRO endorsed project, 32 experts in lung cancer radiotherapy contributed to a modified Delphi consensus process. We assessed potential adaptations of radiotherapy in two pandemic scenarios. The first, an early pandemic scenario of risk mitigation, is characterized by an altered risk-benefit ratio of radiotherapy for lung cancer patients due to their increased susceptibility for severe COVID-19 infection, and minimization of patient travelling and exposure of radiotherapy staff. The second, a later pandemic scenario, is characterized by reduced radiotherapy resources requiring patient triage. Six common lung cancer cases were assessed for both scenarios: peripherally located stage I NSCLC, locally advanced NSCLC, postoperative radiotherapy after resection of pN2 NSCLC, thoracic radiotherapy and prophylactic cranial irradiation for limited stage SCLC and palliative thoracic radiotherapy for stage IV NSCLC.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>In a risk-mitigation pandemic scenario, efforts should be made not to compromise the prognosis of lung cancer patients by departing from guideline-recommended radiotherapy practice. In that same scenario, postponement or interruption of radiotherapy treatment of COVID-19 positive patients is generally recommended to avoid exposure of cancer patients and staff to an increased risk of COVID-19 infection. In a severe pandemic scenario characterized by reduced resources, if patients must be triaged, important factors for triage include potential for cure, relative benefit of radiation, life expectancy, and performance status. Case-specific consensus recommendations regarding multimodality treatment strategies and fractionation of radiotherapy are provided.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>This joint ESTRO-ASTRO practice recommendation established pragmatic and balanced consensus recommendations in common clinical scenarios of radiotherapy for lung cancer in order to address the challenges of the COVID-19 pandemic.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32589990</PMID><DateCompleted><Year>2020</Year><Month>07</Month><Day>08</Day></DateCompleted><DateRevised><Year>2020</Year><Month>07</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1879-355X</ISSN><JournalIssue CitedMedium="Internet"><Volume>107</Volume><Issue>4</Issue><PubDate><Year>2020</Year><Month>07</Month><Day>15</Day></PubDate></JournalIssue><Title>International journal of radiation oncology, biology, physics</Title><ISOAbbreviation>Int. J. Radiat. Oncol. Biol. Phys.</ISOAbbreviation></Journal><ArticleTitle>Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement.</ArticleTitle><Pagination><MedlinePgn>631-640</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0360-3016(20)31136-6</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ijrobp.2020.05.012</ELocationID><Abstract><AbstractText Label="BACKGROUND">The COVID-19 pandemic has caused radiotherapy resource pressures and led to increased risks for lung cancer patients and healthcare staff. An international group of experts in lung cancer radiotherapy established this practice recommendation pertaining to whether and how to adapt radiotherapy for lung cancer in the COVID-19 pandemic.</AbstractText><AbstractText Label="METHODS">For this ESTRO & ASTRO endorsed project, 32 experts in lung cancer radiotherapy contributed to a modified Delphi consensus process. We assessed potential adaptations of radiotherapy in two pandemic scenarios. The first, an early pandemic scenario of risk mitigation, is characterized by an altered risk-benefit ratio of radiotherapy for lung cancer patients due to their increased susceptibility for severe COVID-19 infection, and minimization of patient travelling and exposure of radiotherapy staff. The second, a later pandemic scenario, is characterized by reduced radiotherapy resources requiring patient triage. Six common lung cancer cases were assessed for both scenarios: peripherally located stage I NSCLC, locally advanced NSCLC, postoperative radiotherapy after resection of pN2 NSCLC, thoracic radiotherapy and prophylactic cranial irradiation for limited stage SCLC and palliative thoracic radiotherapy for stage IV NSCLC.</AbstractText><AbstractText Label="RESULTS">In a risk-mitigation pandemic scenario, efforts should be made not to compromise the prognosis of lung cancer patients by departing from guideline-recommended radiotherapy practice. In that same scenario, postponement or interruption of radiotherapy treatment of COVID-19 positive patients is generally recommended to avoid exposure of cancer patients and staff to an increased risk of COVID-19 infection. In a severe pandemic scenario characterized by reduced resources, if patients must be triaged, important factors for triage include potential for cure, relative benefit of radiation, life expectancy, and performance status. Case-specific consensus recommendations regarding multimodality treatment strategies and fractionation of radiotherapy are provided.</AbstractText><AbstractText Label="CONCLUSION">This joint ESTRO-ASTRO practice recommendation established pragmatic and balanced consensus recommendations in common clinical scenarios of radiotherapy for lung cancer in order to address the challenges of the COVID-19 pandemic.</AbstractText><CopyrightInformation>Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Guckenberger</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Switzerland. Electronic address: Matthias.Guckenberger@usz.ch.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Belka</LastName><ForeName>Claus</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, LMU Klinikum, LMU Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bezjak</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bradley</LastName><ForeName>Jeffrey</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Daly</LastName><ForeName>Megan E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, Sacramento, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>DeRuysscher</LastName><ForeName>Dirk</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology (Maastro Clinic), Maastricht University Medical Center(+), GROW Research Institute, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dziadziuszko</LastName><ForeName>Rafal</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Dept. of Oncology and Radiotherapy, Medical University of Gdansk, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Faivre-Finn</LastName><ForeName>Corinne</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Division of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Flentje</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, University Hospital Würzburg, JMU Würzburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gore</LastName><ForeName>Elizabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Medical College of Wisconsin and Zablocki VAMC, Milwaukee, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Higgins</LastName><ForeName>Kristin A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Iyengar</LastName><ForeName>Puneeth</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kavanagh</LastName><ForeName>Brian D</ForeName><Initials>BD</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, University of Colorado, Aurora, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kumar</LastName><ForeName>Sameera</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Le Pechoux</LastName><ForeName>Cecile</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lievens</LastName><ForeName>Yolande</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Ghent University Hospital and Ghent University, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lindberg</LastName><ForeName>Karin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Head, Neck, Lung and Skin Cancer, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McDonald</LastName><ForeName>Fiona</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Royal Marsden Hospital, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ramella</LastName><ForeName>Sara</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Radiation Oncology, Campus Bio-Medico University of Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rengan</LastName><ForeName>Ramesh</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, University of Washington School of Medicine, Seattle, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ricardi</LastName><ForeName>Umberto</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Department of Oncology, University of Turin, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rimner</LastName><ForeName>Andreas</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rodrigues</LastName><ForeName>George B</ForeName><Initials>GB</Initials><AffiliationInfo><Affiliation>Division of Radiation Oncology, Western University, London, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schild</LastName><ForeName>Steven E</ForeName><Initials>SE</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Mayo Clinic, Phoenix, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Senan</LastName><ForeName>Suresh</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Amsterdam UMC, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Simone</LastName><ForeName>Charles B</ForeName><Initials>CB 2nd</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, New York Proton Center and Memorial Sloan Kettering Cancer Center, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Slotman</LastName><ForeName>Ben J</ForeName><Initials>BJ</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Amsterdam UMC, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stuschke</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Radiotherapy, University Duisburg-Essen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Videtic</LastName><ForeName>Greg</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Cleveland Clinic Lerner College of Medicine of Case Western University, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Widder</LastName><ForeName>Joachim</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yom</LastName><ForeName>Sue S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, University of California San Francisco, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Palma</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Division of Radiation Oncology, Western University, London, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Int J Radiat Oncol Biol Phys</MedlineTA><NlmUniqueID>7603616</NlmUniqueID><ISSNLinking>0360-3016</ISSNLinking></MedlineJournalInfo><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D032921" MajorTopicYN="Y">Consensus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008175" MajorTopicYN="N">Lung Neoplasms</DescriptorName><QualifierName UI="Q000532" MajorTopicYN="Y">radiotherapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008495" MajorTopicYN="Y">Medical Oncology</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017410" MajorTopicYN="Y">Practice Guidelines as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012308" MajorTopicYN="N">Risk Management</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012955" MajorTopicYN="Y">Societies, Medical</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014218" MajorTopicYN="N">Triage</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>04</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>04</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>6</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>7</Month><Day>9</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>6</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32589990</ArticleId><ArticleId IdType="pii">S0360-3016(20)31136-6</ArticleId><ArticleId IdType="doi">10.1016/j.ijrobp.2020.05.012</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>France</li><li>Italie</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Canton de Zurich</li><li>Grand Londres</li><li>Grand Manchester</li><li>Ontario</li><li>Pennsylvanie</li><li>Svealand</li><li>Texas</li><li>État de New York</li></region><settlement><li>Dallas</li><li>Londres</li><li>Manchester</li><li>Philadelphie</li><li>Stockholm</li><li>Toronto</li><li>Villejuif</li><li>Zurich</li></settlement><orgName><li>Université de Toronto</li><li>Université de Zurich</li></orgName></list><tree><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Guckenberger, Matthias" sort="Guckenberger, Matthias" uniqKey="Guckenberger M" first="Matthias" last="Guckenberger">Matthias Guckenberger</name></region></country><country name="Allemagne"><noRegion><name sortKey="Belka, Claus" sort="Belka, Claus" uniqKey="Belka C" first="Claus" last="Belka">Claus Belka</name></noRegion><name sortKey="Flentje, Michael" sort="Flentje, Michael" uniqKey="Flentje M" first="Michael" last="Flentje">Michael Flentje</name><name sortKey="Stuschke, Martin" sort="Stuschke, Martin" uniqKey="Stuschke M" first="Martin" last="Stuschke">Martin Stuschke</name></country><country name="Canada"><region name="Ontario"><name sortKey="Bezjak, Andrea" sort="Bezjak, Andrea" uniqKey="Bezjak A" first="Andrea" last="Bezjak">Andrea Bezjak</name></region><name sortKey="Palma, David" sort="Palma, David" uniqKey="Palma D" first="David" last="Palma">David Palma</name><name sortKey="Rodrigues, George B" sort="Rodrigues, George B" uniqKey="Rodrigues G" first="George B" last="Rodrigues">George B. Rodrigues</name></country><country name="États-Unis"><noRegion><name sortKey="Bradley, Jeffrey" sort="Bradley, Jeffrey" uniqKey="Bradley J" first="Jeffrey" last="Bradley">Jeffrey Bradley</name></noRegion><name sortKey="Daly, Megan E" sort="Daly, Megan E" uniqKey="Daly M" first="Megan E" last="Daly">Megan E. Daly</name><name sortKey="Gore, Elizabeth" sort="Gore, Elizabeth" uniqKey="Gore E" first="Elizabeth" last="Gore">Elizabeth Gore</name><name sortKey="Higgins, Kristin A" sort="Higgins, Kristin A" uniqKey="Higgins K" first="Kristin A" last="Higgins">Kristin A. Higgins</name><name sortKey="Iyengar, Puneeth" sort="Iyengar, Puneeth" uniqKey="Iyengar P" first="Puneeth" last="Iyengar">Puneeth Iyengar</name><name sortKey="Kavanagh, Brian D" sort="Kavanagh, Brian D" uniqKey="Kavanagh B" first="Brian D" last="Kavanagh">Brian D. Kavanagh</name><name sortKey="Kumar, Sameera" sort="Kumar, Sameera" uniqKey="Kumar S" first="Sameera" last="Kumar">Sameera Kumar</name><name sortKey="Rengan, Ramesh" sort="Rengan, Ramesh" uniqKey="Rengan R" first="Ramesh" last="Rengan">Ramesh Rengan</name><name sortKey="Rimner, Andreas" sort="Rimner, Andreas" uniqKey="Rimner A" first="Andreas" last="Rimner">Andreas Rimner</name><name sortKey="Schild, Steven E" sort="Schild, Steven E" uniqKey="Schild S" first="Steven E" last="Schild">Steven E. Schild</name><name sortKey="Simone, Charles B" sort="Simone, Charles B" uniqKey="Simone C" first="Charles B" last="Simone">Charles B. Simone</name><name sortKey="Videtic, Greg" sort="Videtic, Greg" uniqKey="Videtic G" first="Greg" last="Videtic">Greg Videtic</name><name sortKey="Yom, Sue S" sort="Yom, Sue S" uniqKey="Yom S" first="Sue S" last="Yom">Sue S. Yom</name></country><country name="Pays-Bas"><noRegion><name sortKey="Deruysscher, Dirk" sort="Deruysscher, Dirk" uniqKey="Deruysscher D" first="Dirk" last="Deruysscher">Dirk Deruysscher</name></noRegion><name sortKey="Senan, Suresh" sort="Senan, Suresh" uniqKey="Senan S" first="Suresh" last="Senan">Suresh Senan</name><name sortKey="Slotman, Ben J" sort="Slotman, Ben J" uniqKey="Slotman B" first="Ben J" last="Slotman">Ben J. Slotman</name></country><country name="Pologne"><noRegion><name sortKey="Dziadziuszko, Rafal" sort="Dziadziuszko, Rafal" uniqKey="Dziadziuszko R" first="Rafal" last="Dziadziuszko">Rafal Dziadziuszko</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Faivre Finn, Corinne" sort="Faivre Finn, Corinne" uniqKey="Faivre Finn C" first="Corinne" last="Faivre-Finn">Corinne Faivre-Finn</name></region><name sortKey="Mcdonald, Fiona" sort="Mcdonald, Fiona" uniqKey="Mcdonald F" first="Fiona" last="Mcdonald">Fiona Mcdonald</name></country><country name="France"><noRegion><name sortKey="Le Pechoux, Cecile" sort="Le Pechoux, Cecile" uniqKey="Le Pechoux C" first="Cecile" last="Le Pechoux">Cecile Le Pechoux</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Lievens, Yolande" sort="Lievens, Yolande" uniqKey="Lievens Y" first="Yolande" last="Lievens">Yolande Lievens</name></noRegion></country><country name="Suède"><region name="Svealand"><name sortKey="Lindberg, Karin" sort="Lindberg, Karin" uniqKey="Lindberg K" first="Karin" last="Lindberg">Karin Lindberg</name></region></country><country name="Italie"><noRegion><name sortKey="Ramella, Sara" sort="Ramella, Sara" uniqKey="Ramella S" first="Sara" last="Ramella">Sara Ramella</name></noRegion><name sortKey="Ricardi, Umberto" sort="Ricardi, Umberto" uniqKey="Ricardi U" first="Umberto" last="Ricardi">Umberto Ricardi</name></country><country name="Autriche"><noRegion><name sortKey="Widder, Joachim" sort="Widder, Joachim" uniqKey="Widder J" first="Joachim" last="Widder">Joachim Widder</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidFranceV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000915 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000915 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= CovidFranceV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32589990
|texte= Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32589990" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidFranceV1
| This area was generated with Dilib version V0.6.37. |  |